What is the cause of primary hyperparathyroidism?

Answer 1

The etiology of hyperparathyroidism is increased production of the parathyroid hormone. The levels of calcium and phosphorus are governed by the secretion pf PTH, parathyroid hormone, which regulates body temperature.

Answer 2

If the parathyroid glands secrete too much hormone, as happens in primary hyperparathyroidism, the balance is disrupted: Blood calcium rises. This condition of excessive calcium in the blood, called hypercalcemia, is what usually signals the doctor that something may be wrong with the parathyroid glands. In 85 percent of people with primary hyperparathyroidism, a benign tumor called an adenoma has formed on one of the parathyroid glands, causing it to become overactive. Benign tumors are noncancerous. In most other cases, the excess hormone comes from two or more enlarged parathyroid glands, a condition called hyperplasia. Very rarely, hyperparathyroidism is caused by cancer of a parathyroid gland.This excess PTH triggers the release of too much calcium into the bloodstream. The bones may lose calcium, and too much calcium may be absorbed from food. The levels of calcium may increase in the urine, causing kidney stones. PTH also lowers blood phosphorus levels by increasing excretion of phosphorus in the urine.

Answer 3

Low calcium levels signal the parathyroid gland to release more hormone. Tumors both benign and malignant can also cause the elevation of parathyroid hormone, because the gland is malfunctioning and auto-regulation is left unchecked.

Answer 4

Spontaneous nerve depolarization causing muscular spasms, twitches and convulsions, Trousseau sign- Cuffing the arm leads to irreversible flexion of fingers, Chvostek sign- Tapping the facial nerve branches at the lower margin of the jaw produces contraction of facial muscles.

Answer 5

Hyperparathyroidism is caused by the presence of a tumor or mass, typically in one of the four parathyroid glands in the neck area. These glands lay just behind the thyroid gland. The parathyroid gland, stimulates the anterior pituitary gland to release the hormone called parathormone.

This hormone "talks" to the skeletal system to release calcium into the bloodstream. Too much hormone means too much calcium is being released into your system. Ninety-nine percent of the time, if you have consistent high blood calcium, you have hyperparathyroidism.

Hyperparathyroidism causes a wide range of symptoms which varies from person to person, however can typically cause fatigue, bone and muscle pain, irritability and crankiness, fluctuations in blood pressure, and heart arrhythmia's. Additionally, if left untreated, everyone who has hyperparathyroidism will eventually get osteoporosis.

Answer 6

Primary hyperparathyroidism is usually caused by a benign tumor on one of the parathyroid glands, leading to an overproduction of parathyroid hormone (PTH). This results in increased levels of calcium in the blood, leading to symptoms such as fatigue, bone pain, kidney stones, and weakened bones.

Answer 7

Primary hyperparathyroidism occurs as a malfunction of one of the glands, usually as a result of a benign tumor called an adenoma.