A point mutation is where a single letter is the only thing changed in the DNA sequence. Lets say your phone number (or DNA code) was 483-1839 and you mistakely told someone that your phone number was 483-1835. that one digit is enough to make that person dial the wrong number (or cause a mutation in DNA.) For example suppose your DNA sequence was ACT GCT, a point mutation would just be a change in one of those bases (or letters), so it could end up something like : ACT ACT.
EX: GTA CTG CAA-----> (point mutation) -----> GTA GTG CAA
A frameshift mutation is generally much more serious and will cause a change all the way down a DNA sequence, making each codon (or every group of three bases) a different sequence, not just in one point or base like a point mutation, that would only slightly change the sequence of a single codon. A frameshift mutation happens not when a DNA base is simply changed, but when a whole base is added or deleted from the sequence of DNA. For example lets suppose your DNA sequence is GTA CCT AGG. In a frameshift mutation a whole base would be added somewhere in that sequence, making it look something like this: GTAT CCT AGG. Since it is impossible though to have 4 bases in a codon, your body would automatically shift every letter down one, even to the next codon in the sequence, to make room for this new base. In the end the final product would look something like this: GTA TCC TAG (with the left over G being the first base in the next codon, and so on).
EX: CAG TTC CTG GAA -----> (frameshift muation) -----> CAG TTA CCT GGA
As you can see the frameshift mutation would leave the mutated DNA vastly more different from its parent DNA (that it was replicated from), then a point mutation would, though in both cases the DNA would still be different/mutated. This is because the codons would be more considerbaly changed with the frameshift (where now the sequence in every codon in different), rather than in a point mutation (where only one of the codons would be different).
Hope this helps all you HS Bio 1 people like myself out there, or anyone else studying this subject.
-- K.J.S
Missense mutation: changes one sense codon to another, resulting in incorporation of amino acid.Nonsense mutation: changes a sense codon into a stop (or nonsense) codon, resulting in premature termination.
A frame-shift mutation.
A frame shift mutation destroys the correct sequence of amino acids from the point of the mutation. The protein produced by a frame shift mutation would more than likely be nonfunctional.
Insertion & deletion also known as frameshift mutationsubstitutionduplication mutationtranslocationGlad we could assist.
false
Missense mutation: changes one sense codon to another, resulting in incorporation of amino acid.Nonsense mutation: changes a sense codon into a stop (or nonsense) codon, resulting in premature termination.
Generally, a germ line mutation or sex cell mutation. Could be anything from a point mutation, one amino acid difference, to a whole frame shift mutation.
A point mutation causes a change in the amino acid sequence creating a new type of protein. The mutations are categorized functionally as nonsense, missense and silent mutations.
A frame-shift mutation.
a 540 difference
A frame shift mutation destroys the correct sequence of amino acids from the point of the mutation. The protein produced by a frame shift mutation would more than likely be nonfunctional.
Nonsense answer deleted.
A point mutation is never a frameshift mutation because it involves the substitution of a single nucleotide for another rather than the insertion or deletion of nucleotides that would disrupt the reading frame of a gene.
Adding or subtracting just one nucleotide would cause a frame shift mutation.
A frame is the skeleton of a car without the mountings, were as a chasis is a mounted frame.
There is no difference
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