to reduce to particles, fragments, or parts; break up ordestroy the cohesion of: Rocks are disintegrated by frost andrain.
Tablets or capsules taken orally remain one of the most effective means of treatment available. The effectiveness of such dosage forms relies on the drug dissolving in the fluids of the gastrointestinal tract prior to absorption into the systemic circulation. The rate of dissolution of the tablet or capsule is therefore crucial.
- disintegration of materials - help for dissolution - cleaning of objects - help for some chemical reactions - pulverization of liquids
basic principal of dissolution run as per individuala monograph and know the % of active drugs in sample
Disintegration is the breakdown of a solid dosage form into smaller particles, often facilitated by mechanical forces such as chewing or stomach contractions. Dissolution is the process in which the small particles of the drug are released into a liquid medium and become solubilized. Both processes are essential for the drug to be absorbed and have a therapeutic effect in the body.
A bacteriophage is a kind of virus that infects and kills bacteria.a virus that attacks bacteria
Taking 900ml of water as the disintegration medium in a disintegration test is commonly used to simulate the conditions of the stomach where the dosage form is expected to disintegrate. This volume is considered sufficient to provide the necessary agitation and dissolution properties needed for the test. It also helps ensure reproducibility and accuracy in the disintegration test results.
Dissolution is the process by which a drug substance dissolves in a liquid medium, such as gastric fluid, to become available for absorption. Disintegration, on the other hand, refers to the breaking apart of the tablet or capsule into smaller particles. Disintegration occurs first to increase the surface area for dissolution to happen efficiently.
lysis
The opposite would be dissipation, dissolution, disintegration.
Dissociation refers to the separation of components or elements, while dissolution refers to the breaking down or dispersal of a substance into smaller parts.
- disintegration of materials - help for dissolution - cleaning of objects - help for some chemical reactions - pulverization of liquids
basic principal of dissolution run as per individuala monograph and know the % of active drugs in sample
Disintegration is the breakdown of a solid dosage form into smaller particles, often facilitated by mechanical forces such as chewing or stomach contractions. Dissolution is the process in which the small particles of the drug are released into a liquid medium and become solubilized. Both processes are essential for the drug to be absorbed and have a therapeutic effect in the body.
Disintegration is fragmentation of rock and there is no chemical change during or after this process. Decomposition is resulting in the destruction of some or all of the unstable minerals and thus chemical change occur and new minerals are formed.
Dissolution is the process where a solid substance dissolves in a liquid to form a solution, while dissociation is the process where a compound breaks apart into its individual ions in a solution.
A bacteriophage is a kind of virus that infects and kills bacteria.a virus that attacks bacteria
Taking 900ml of water as the disintegration medium in a disintegration test is commonly used to simulate the conditions of the stomach where the dosage form is expected to disintegrate. This volume is considered sufficient to provide the necessary agitation and dissolution properties needed for the test. It also helps ensure reproducibility and accuracy in the disintegration test results.
Melting and dissolution are physical processes; but some chemists consider dissolution as a chemical process.