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Antimycin A inhibits the mitochondrial respiratory complex III. In cell culture, antimycin A can cause an increase in production of O2 and H2O2, which play a role in the production of the hydroxyl radical.

For more info:

Sheu, S. et al. "Targeting antioxidants to mitochondria: a new therapeutic direction." Biochim. Biophys. Acta. 1762(2006): 256-265.

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