What is the effect of hypertonic solution on rbc?

Answer 1

A blood cell immersed in a hypertonic solution will cause water to move out of the cell, thereby causing it to shrivel. Osmotic pressure is water's tendency to seek to equalize its own concentration across a semipermeable membrane (like the cell membrane of a blood cell). So in a hypertonic solution (relative to the solution inside the blood cell), there are less particles of water per particle of solute. This means the water concentration inside the blood cell is higher, and mother nature will have none of that. So water will move out of the cell, seeking to equalize its concentration across the cell membrane. If the membrane is also permeable to solutes in the hypotonic solution, they will move across the membrane following their own chemical and electromagnetic concentration gradients.

Answer 2

A hypertonic solution will cause red blood cells to shrink and lose water due to osmosis, as water moves from a region of higher water concentration (inside the cell) to lower water concentration (outside the cell). This can lead to the cells shriveling up or even bursting (hemolysis) in extreme cases.