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. The transformation of glucose into fructose by the enzyme glucose isomerase, was carried out in two different types suspended-enzyme bioreactors: 1) CSTR, and 2) plug flow reactor. The process obeys Michaelis-Menten kinetics. The following parameters and kinetic constants were kept the same in both bioreactors: $ So (input substrate concentration) = 1.0 mMol/L; $ F (volumetric flow rate) = 1.0 m3/h; $ Km = 7x10-4 Mol/L; $ Vmax = 0.2 mMol/(L.h) Determine: $ Volume of CSTR for 50% conversion of glucose; $ Volume of PFR for 50% conversion of glucose; $ Volumes of CSTR and PFR in series (assume that the volumes are equal) in two cases: $ first CSTR $ first PFR 2. Calculate the volume of a stirred tank bioreactor containing the same enzyme, but immobilized on the surface of a flat-geometry support. The value of the mass-transfer coefficient is 0.6 h-1. The values of the rest of process parameters are the same as above.

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