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The cell membrane behave as a living barrier for the flow of movement of substance in and out of the cell. Cell membrane containg small pore of approximately 8-10 Ao wide pores. Thus the molecule only of this size and smaller then this can pass through the cell membrane in bulk and permeable transport. The transport although mainly occurs in two ways by passive transport in which no energy is needed and molecules or substances are transported in flow of concentration gradient. Second is active transport in which energy is needed (in eukaryotes energy is provided by ATP and in prokaryotes it is generally comes from proton motive force) and substance or molecules move against the concentration gradient e.g. Na-K exchange pump.

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