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The large number before a molecule in a chemical equation is called a coefficient. It indicates the number of molecules or moles of that substance involved in the reaction. Coefficients are used to balance chemical equations, ensuring that the number of atoms for each element is the same on both sides of the equation. For example, in the equation 2H₂ + O₂ → 2H₂O, the coefficient "2" before H₂ and H₂O signifies that there are two molecules of hydrogen and two molecules of water involved in the reaction.

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