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In neuronal transmission, the normal order of activation begins with the generation of an action potential in the presynaptic neuron, typically triggered by the influx of sodium ions through voltage-gated sodium channels. This action potential travels down the axon to the axon terminals, where it stimulates the release of neurotransmitters into the synaptic cleft. The neurotransmitters then bind to receptors on the postsynaptic neuron, leading to depolarization and potentially generating an action potential in that neuron. This sequence facilitates communication between neurons in the nervous system.

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1w ago

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