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It goes to hell.

EDIT: yeah....no it doesn't.

When no oxygen is present you can not have oxidative phosphorylation because you need the oxygen to accept the 2 electrons at the end of the electron transport chain. No Oxygen = No electron transport chain. Therefore the cell does not go into the Kreb's cycle either when it senses low oxygen levels because it eventually hits a "dead end" in the electron transport chain.

The only other option left is Glycolysis which is truly anerobic. However this only produces 2 ATP vs 38 through the other process. The way it produces ATP anerobically is once it gets to the end of glycolysis NAD gets reduced. However, we have a LIMITED amount of NAD in our cell and as this is our last resort for energy we can not have all of the NAD reduced and need to oxidate it (so that we can keep the process going a little longer) by forming lactic acid. Forming lactic acid allows us to keep using the handful of NADs that we do have giving us a little bit of extra time to find an oxygenated environment.

If you continue to exercise/function under anaerobic conditions your overall energy expenditure will be greater than your ATP production and your cells would start to die. Which is why when you strangle someone you're cutting off their oxygen supply and...they die.

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