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Purmorphamine, under the IUPAC name 9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine, is a cell-permeable 6,9-trisubstituted purine which directly binds and activates Smoothened (in HEK293T cell：IC50= ~ 1.5 μM ).So it has been shown to activate the Hedgehog (Hh) signaling pathway which is important for regulating embryonic patterning, stem cell renewal, and tissue regeneration. I found the answer from the website of BOC Sciences.
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What is the purpose of purifying a protein?
Purifying a protein helps to isolate and concentrate the protein of interest from a complex sample, removing unwanted contaminants. This allows for further characterization and analysis of the protein's structure, function, and interactions. Purified proteins are also crucial for biological assays, structural studies, and therapeutic applications.
What are the classifications of inorganic pharmaceuticals based on their applications and therapeutic uses?
Inorganic pharmaceuticals can be classified based on their applications into antacids, electrolytes, and anticancer agents. Additionally, they can be classified based on therapeutic uses such as antifungals, antivirals, and anti-inflammatories.
What are therapeutic proteins?
There are many proteins essential to good health that some people cannot produce because of genetic defects. These proteins include various blood-clotting factors causing hemophilia, insulin (resulting in diabetes), growth hormone (resulting in lack of proper growth), and other proteins, the administration of which corrects the pathological conditions or results in other therapeutic benefits. such proteins are termed as therapeutic proteins
What is a synthetic immunoglobulin?
A synthetic immunoglobulin is an artificially created antibody that mimics the function of natural antibodies in the immune system. It is designed to target specific antigens and trigger an immune response to fight off pathogens or diseases. Synthetic immunoglobulins are being developed for therapeutic purposes in treating various medical conditions.
How do you produce therapeutic proteins by plants?
Therapeutic proteins can be produces by finding the gene that encodes the protein of interest and engineering it into a plant genome and placing it under the control of a strong promoter. However, if the protein of interest id very complex and involves a lot of post translational modifications, an animal system would be well suited for making the protein rather than a plant system. Not many researchers use a plant system to create therapeutic protein due to low yield and difficulty in purifying the target protein from the plant material
What is the purpose of a therapeutic drug?
The purpose of a therapeutic drug is to treat, manage, or cure a medical condition, illness, or disease. These drugs are designed to alleviate symptoms, improve quality of life, or restore normal bodily function in patients.
Difference between therapeutic and non therapeutic technique?
Therapeutic is an immediate physical treatment, non-therapeutic is a treatment such as sterilisation
How would you define the therapeutic dosage?
The therapeutic dosage is the amount of a therapeutic agent which causes the therapeutic effect. This is prescribed by qualified therapists for varied conditions.
What are the benefits of incorporating therapeutic exercise for elderly individuals into their daily routine?
Incorporating therapeutic exercise into the daily routine of elderly individuals can improve their strength, balance, flexibility, and overall physical function. This can help prevent falls, reduce pain, and enhance their quality of life.
Fodds for therapeutic diet?
foods for therapeutic diet
What has the author Clare T Garrard written?
Clare T. Garrard has written: 'The effect of therapeutic touch on stress reduction and immune function in persons with AIDS' -- subject(s): AIDS (Disease), Patients, Psychological aspects, Psychological aspects of AIDS (Disease), Therapeutic use, Touch
What is a sentence for the word therapeutic?
Therapeutic refers to the healing of disease. The hot bath was therapeutic for his arthritis.
Therapeutic in a sentence?
A relaxing massage can be very therapeutic for a stressed individual.
What are the principles and practices of therapeutic massage?
Enumerate the practices of therapeutic massage
What is the duration of Therapeutic Pink?
The duration of Therapeutic Pink is 360.0 seconds.
Therapeutic blood levels for benadryl?
Therapeutic blood level for benadryl
What is therapeutic procedures?
Therapeutic procedures are procedures that soothe you. Therapeutic procedures don't just soothe you mentally, but physically, too. There are a wide range of therapeutic procedures, which range from massages, to just sitting in a warm bath.
