Pyruvate is initially converted to oxaloacetate in the anabolism of glucose. That molecule in turn is converted to phosphoenolpyruvate.
One glucose molecule is converted to two pyruvate molecules during glycolysis.
In the bridge reaction, also known as the transition step between glycolysis and the Krebs cycle, one molecule of pyruvate is converted into one molecule of acetyl-CoA. During this process, one molecule of NADH is produced for each pyruvate converted. Since each glucose molecule produces two pyruvate molecules, a total of two NADH molecules are generated from the bridge reaction for each glucose molecule. However, no FADH2 is produced in this step.
The products of acetyl CoA formation from a molecule of pyruvate are acetyl CoA, NADH, and carbon dioxide. This process occurs during the mitochondrial pyruvate dehydrogenase complex reaction, where pyruvate is converted to acetyl CoA by a series of enzymatic reactions.
There are three carbon atoms and three oxygen atoms in each pyruvate molecule.
Galactose is converted to glucose-6-phosphate, which can enter glycolysis to produce pyruvate. Pyruvate can then be converted to acetyl-CoA, a molecule that enters the Krebs cycle. This allows galactose-derived metabolites to be utilized in the Krebs cycle for energy production.
Glucose is the raw material. It is converted into pyruvate.
One glucose molecule is converted to two pyruvate molecules during glycolysis.
During the oxidation of pyruvate, a total of 2 carbon atoms are lost in the form of carbon dioxide. Pyruvate, a 3-carbon molecule, is converted into acetyl-CoA, which is a 2-carbon molecule, leading to the release of 2 carbon atoms as CO2.
Glycolysis, in which glucose molecule is converted into pyruvic acid (pyruvate).
In the bridge reaction, also known as the transition step between glycolysis and the Krebs cycle, one molecule of pyruvate is converted into one molecule of acetyl-CoA. During this process, one molecule of NADH is produced for each pyruvate converted. Since each glucose molecule produces two pyruvate molecules, a total of two NADH molecules are generated from the bridge reaction for each glucose molecule. However, no FADH2 is produced in this step.
The products of acetyl CoA formation from a molecule of pyruvate are acetyl CoA, NADH, and carbon dioxide. This process occurs during the mitochondrial pyruvate dehydrogenase complex reaction, where pyruvate is converted to acetyl CoA by a series of enzymatic reactions.
Pyruvate is the molecule that is the output of glycolysis and is quickly converted to Acetyl CoA before entering the citric acid cycle. This conversion occurs in the mitochondria through a process called pyruvate decarboxylation, where pyruvate loses a carbon dioxide molecule and forms Acetyl CoA.
Acetyl CoA
There are three carbon atoms and three oxygen atoms in each pyruvate molecule.
Galactose is converted to glucose-6-phosphate, which can enter glycolysis to produce pyruvate. Pyruvate can then be converted to acetyl-CoA, a molecule that enters the Krebs cycle. This allows galactose-derived metabolites to be utilized in the Krebs cycle for energy production.
Pyruvate is a three-carbon molecule derived from glucose metabolism. It plays a key role in cellular respiration, where it is converted into acetyl-CoA to enter the citric acid cycle for further energy generation.
During the transition reaction, also known as the pyruvate decarboxylation process, each molecule of pyruvate is converted into one molecule of acetyl-CoA, resulting in the release of one molecule of carbon dioxide. Since each glucose molecule produces two pyruvate molecules during glycolysis, a total of two molecules of carbon dioxide are produced during the transition reaction for one glucose molecule.