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The movement of a segment from one chromosome to another non-homologous chromosome is primarily facilitated by processes such as translocation, which often occurs during DNA repair or recombination events. This can involve the action of specific enzymes, like transposases or integrases, which facilitate the insertion of DNA segments into new locations. Additionally, mechanisms like non-homologous end joining (NHEJ) can also play a role in connecting disparate chromosome segments. These events can lead to genomic rearrangements that may have implications for genetic diversity or disease.

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