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Beta-thalassemia is typically caused by mutations in the HBB gene located on chromosome 11. Common mutations include point mutations, deletions, or insertions in the HBB gene, leading to reduced or absent production of beta-globin chains in hemoglobin. These mutations disrupt the normal structure and function of hemoglobin, resulting in anemia and other symptoms associated with beta-thalassemia.

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1y ago

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Related Questions

What can cause changes in DNA sequences?

mutations


Changes in DNA are called mutations?

That's correct. Mutations are changes in the DNA sequence that can result from errors during DNA replication, exposure to mutagens, or other environmental factors. Mutations can have various effects, ranging from no impact to influencing an organism's traits or health.


How does polymerase prevent mutations?

It checks DNA for errors during replication.


What is a source of genetic variation that refers to a random error in the genetic code?

Mutations involve changes in the DNA code.


Changes in DNA is called?

mutations


Mutations are changes in?

changes in DNA


How can mutations cause genetic mutations in spite of your body's DNA repair enzymes?

Mutagens cause a change in DNA and by this way they can produce mutant DNA repair enzymes.


Mistakes in the DNA are called?

for Plato it isn't A or B the answer is D


What is one way that can occur in a DNA sequence?

Mutations (point mutations, inversions, translocations...) cause changes in DNA Simply stated, a mistake made while DNA copies causes changes in DNA.


What are 4 things that contribute to mutation?

DNA replication errors during cell division can introduce mutations. Exposure to mutagens such as radiation, chemicals, and viruses can cause DNA damage and mutations. Environmental factors like UV light can induce mutations in DNA. Inherited genetic mutations passed down from parents can contribute to mutations in offspring.


What are known as gene mutations and occur at a single point in the DNA sequence?

Gene mutations that occur at a single point in the DNA sequence are called point mutations. These mutations can involve substitutions of one nucleotide for another (missense mutation), insertion of an extra nucleotide (insertion mutation), or deletion of a nucleotide (deletion mutation). Point mutations can have various effects on the resulting protein, ranging from no impact to severe functional changes.


What cell cause mutations?

DNA polymerase