A diuretic that acts at the distal part of the nephron is usually a thiazide or thiazide-like diuretic, such as hydrochlorothiazide or chlorthalidone. These diuretics work by inhibiting sodium and chloride reabsorption in the distal convoluted tubule of the nephron, leading to increased urine output.
Bendroflumethiazide is not a beta-blocker; it is a thiazide diuretic used to treat high blood pressure (hypertension) and reduce excess fluid in the body (edema). Thiazide diuretics work by increasing the excretion of salt and water through the kidneys, which helps to lower blood pressure.
Diuretics promote urine secretion and help to decrease fluid retention. They work by increasing the excretion of water and electrolytes by the kidneys, thus leading to increased urine production. Examples of diuretics include thiazides, loop diuretics, and potassium-sparing diuretics.
The nephron is the functional unit of the kidney responsible for filtering blood and producing urine. It consists of the renal corpuscle (glomerulus and Bowman's capsule), proximal convoluted tubule, loop of Henle, distal convoluted tubule, and collecting duct. These components work together to regulate electrolyte balance and eliminate waste products from the body.
4cc of out put in 24 hour period time
A diuretic that acts at the distal part of the nephron is usually a thiazide or thiazide-like diuretic, such as hydrochlorothiazide or chlorthalidone. These diuretics work by inhibiting sodium and chloride reabsorption in the distal convoluted tubule of the nephron, leading to increased urine output.
Loop diuretics work by restraining the sodium-potassium-chloride cotransporter. Thiazide diuretics restrain the sodium-chloride transporter. Carbonic anhydrase inhibiting diuretics work by restraining bicarbonate transport.
drugs in this class appear to lower blood pressure through several mechanisms. By promoting sodium loss they lower blood volume.
Bendroflumethiazide is not a beta-blocker; it is a thiazide diuretic used to treat high blood pressure (hypertension) and reduce excess fluid in the body (edema). Thiazide diuretics work by increasing the excretion of salt and water through the kidneys, which helps to lower blood pressure.
It depends on the channel/transporter being blocked. For example, it's well established that a type of diuretic called a loop diuretic (eg, furosemide) causes hypercalciuria, a fancy term for excess calcium in the urine. Loop diuretics work by blocking a sodium-potassium-chloride transporter in the kidney, and indirectly result in decreased calcium reabsorption from the urine. Because most kidney stones are made of calcium, the excess urinary calcium caused by loop diuretics can predispose people to kidney stones. By contrast, thiazide diuretics (eg, hydrochlorothiazide) commonly used to treat high blood pressure often cause hypocalciuria, which is decreased urinary calcium. Thiazides work by blocking a sodium-chloride transporter in the kidney, indirectly causing increased calcium reabsorption so less ends up in the urine. So thiazide is a reasonable medication to use for treating high blood pressure in patients prone to kidney stones. Thiazide and loop diuretics aren't technically "channel blockers", but I'm assuming you're using the term loosely. Perhaps I'm wrong though.
The dialysis machine is time - consuming while the properly funtioning nephron can get work done quickly
Diuretics work in the region of the collecting ducts, but on the ducts themselves. They inhibit ADH from causing water to be reabsorbed in the distal tubules and that produces more urine output.
Diuretics promote urine secretion and help to decrease fluid retention. They work by increasing the excretion of water and electrolytes by the kidneys, thus leading to increased urine production. Examples of diuretics include thiazides, loop diuretics, and potassium-sparing diuretics.
A Nephron is the basic structural and functional unit of the kidney. It's not a molecule, more likely a small portion of the kidney that helps the kidney work.
ALL diuretics are renal poisons, (some worse than others, I admit) and in failure your kidneys are already in enough trouble.from Japonesitaloca:I disagree. Way too general of a statement.Diuretics: actually diuretics are commonly used in chronic renal failure and are effective. High doses of furosemide (LASIX) areoften given with good results (doses have to be high cuz renal failure makes the kidneys less responsive to it)...if effects areinsufficient with LASIX, we often give another thiazide type diuretic metolazone (ZAROXYLYN) 30 min. before the lasix toincrease the effects--the 2 drugs together are a lot more effective.In acute renal failure, it has been shown the diuretics have had negative effects (increased mortality, non-recovery of kidneys, increased hospital days)-but the attraction in diuretics in ARF lies in the excretion of sodium and water
Potassium
It reduces the blood volume through greater excretion of water by the kidneys.