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How can you increase tablet hardness without changing formulation?

Increasing tablet hardness without changing the formulation can be achieved by adjusting the compression force during tablet manufacturing. By increasing the compression force, the particles in the formulation will be more tightly packed together, resulting in harder tablets. Alternatively, using a smaller tablet punch size can also increase tablet hardness without altering the formulation.


What effect does dissolving antacid tablet have on water temperature?

Dissolving an antacid tablet in water can have an endothermic effect, meaning it absorbs heat from the surroundings and lowers the temperature of the water. This happens because the reaction between the antacid and water requires energy to break the bonds in the tablet and dissolve it.


How does the water temperature affect the dissolving time of a frizzy tablet?

Water temperature can affect the dissolving time of a fizzing tablet because higher temperatures increase the kinetic energy of water molecules, allowing them to interact more quickly with the tablet. This can result in faster dissolution at higher temperatures compared to lower temperatures.


What is compression technology in pharmaceutical manufacturing?

Compression technology refers to the compression of tablets (pills) during the drug formulation or manufacturing process. Since the most common method of drug delivery is the oral solid dosage form, a great amount of research and time has been put into perfecting the compression technique. There have been recent innovations and advancements in compression equipment to minimize tablet weight variation.


What is the material of construction used for the manufacture of punches and dyes in tablet compression machine in pharmacy industry?

The materials commonly used for manufacturing punches and dies in tablet compression machines in the pharmacy industry are tool steel, carbide, and ceramic. Tool steel is durable and cost-effective, carbide is wear-resistant and long-lasting, while ceramic is known for its high strength and resistance to corrosion. Manufacturers choose the material based on factors like production volume, tablet formulation, and desired tool life.

Related Questions

What is principle of tablet compression machine?

the principle of tablet compression machine is based on hydrollic principle


How an AWC works in tablet compression machine?

The AWC works in tablet compression machine based on the hydraulic principle.


What is the use dry compression method for tablet?

by using the dry compression method for tablets to avoid the moisture present in the tablets


How can you increase tablet hardness without changing formulation?

Increasing tablet hardness without changing the formulation can be achieved by adjusting the compression force during tablet manufacturing. By increasing the compression force, the particles in the formulation will be more tightly packed together, resulting in harder tablets. Alternatively, using a smaller tablet punch size can also increase tablet hardness without altering the formulation.


Hydraulic pressure on tablet compression machine but in result gain hardness on tablet how the pressure is converted into hardness unit?

In the tablet compression machine main principle is compressing the upper & lower puch in a die hole . the hydraulic pressure plays a key role if we increase the hydra. pressue more compressing force on tablet then it becomes more hard.


What is tablet hardness and friability?

what is the tblet hardness,what is its unit ,we aply hydraulic pressure on tablet compression mchine but in result we gain hardness on tablet,how the pressure is converted into hardness unit. Friability refers to the ability of the compressed tablet to avoid fracture and breaking apart during transport.


What should the temperature be for an alka-seltzer tablet dissolve and react?

The Temperature should be at least 40 degree Fahrenheit of higher for it to dissolve any temperature lower will take a long time to react or it will not react at all. The higher the temperature, the faster the dissolving and reacting.


Why single rotary and double rotary tablet compression machine have even and odd different station?

I dont know really


Why odd no of stations in double rotary compression machine?

An odd number of stations in a double rotary compression machine helps to ensure a balanced and symmetrical filling process, which leads to more uniform tablet weights and better tablet quality. This setup reduces the possibility of issues such as capping and weight variation in the tablets.


In which bin should we dispose tablet stripes?

In which colour bin should we dispose tablet stripes and electonic waste?


What do you do if your tablet is locked?

Your tablet should have an area for you to enter your number password. This will unlock it for you.


What factors will make an alka-seltzer tablet dissolve faster?

temperature of water i know for sure if the water is hotter, the tablet will dissovle faster