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What type of mutation in the DNA leads to a single change in the amino acid sequence of the protein?
Yes, it already has by changing the amino acid you have a mutation. That one amino acid counld be in the active site of an enzyme and that one amino acid being changed could result in loss of function or reduction in function of the enzyme. Sickle cell animea is caused by a single such amino acid substiution.
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What type of mutation results in abnormal amino acids sequence?
A missense mutation results in an abnormal amino acid sequence. This type of mutation occurs when a single nucleotide change in the DNA sequence leads to the substitution of one amino acid for another in the protein product. Depending on the specific change, this can impact the protein's function and stability. Other types of mutations, such as nonsense or frameshift mutations, can also disrupt the amino acid sequence but in different ways.
Which genetic change is best described by the following statement A random change in the base sequence of DNA results in an alteration of a polypeptide?
A point mutation is best described by this statement. Point mutations occur when there is a change in a single nucleotide base in the DNA sequence, which can lead to changes in the corresponding amino acid sequence of a polypeptide during protein synthesis.
What is one or two nucleotides that are changed in a certain mutation?
In a point mutation, a change in a single nucleotide can lead to a specific mutation. For example, a substitution mutation occurs when one nucleotide is swapped for another, such as A to T or C to G. This change can result in different amino acids being coded for in the protein sequence.
How a change in the sequence of nucleotides in a strand of DNA might cause a protein to malfunction?
A change in the DNA sequence, such as a point mutation, can result in a different amino acid being incorporated into the protein during translation. This can alter the protein's structure, possibly affecting its function or leading to improper folding. In some cases, the mutation may introduce a premature stop codon, resulting in a truncated and non-functional protein.
What is the point mutation of AGGCGTCCATGA?
A point mutation refers to a change in a single nucleotide in a DNA sequence. In the sequence AGGCGTCCATGA, any alteration of a single base pair would qualify as a point mutation. For example, if the first 'G' were replaced with an 'A', the mutated sequence would be AGGCGTCCATGA → AAGCGTCCATGA.
Can a point mutation be frameshift mutation?
No
Suppose part of an amino acid sequence of a protein changed from tyrosine proline glycine alanine to tyrosine histidine glycine alanine this change was most likely caused by a point mutation called?
This change was most likely caused by a point mutation called a missense mutation. Missense mutations involve the substitution of a single nucleotide in the DNA sequence, leading to a change in one amino acid in the protein sequence. In this case, the substitution of a single nucleotide led to the change from tyrosine to histidine in the protein sequence.
Can a point mutation cause a change in one single nucleotide in a DNA sequence?
Yes, a point mutation can cause a change in one single nucleotide in a DNA sequence.
What is the difference between point and non-synonymous mutation?
A point mutation is a change in a single nucleotide in the genetic code, while a non-synonymous mutation is a type of point mutation that causes an amino acid change in the resulting protein. Non-synonymous mutations can affect the function of the protein, while synonymous mutations do not change the amino acid sequence.
How can a point mutation affect the protein created by the gene?
A point mutation can affect the protein created by a gene by changing a single nucleotide in the gene's DNA sequence. This change can alter the amino acid sequence of the protein, potentially leading to a different protein being produced. This can impact the protein's structure and function, which may result in a variety of effects on the organism.
Which type of mutation results in the formation of a protein with one incorrect amino acid-?
A point mutation, specifically a missense mutation, is responsible for the formation of a protein with one incorrect amino acid. This type of mutation involves a single nucleotide change in the DNA sequence, leading to the substitution of one amino acid in the protein.
Which genetic change is best described by the following statement A random change in the base sequence of DNA results in an alteration of a polypeptide?
A point mutation is best described by this statement. Point mutations occur when there is a change in a single nucleotide base in the DNA sequence, which can lead to changes in the corresponding amino acid sequence of a polypeptide during protein synthesis.
What is one or two nucleotides that are changed in a certain mutation?
In a point mutation, a change in a single nucleotide can lead to a specific mutation. For example, a substitution mutation occurs when one nucleotide is swapped for another, such as A to T or C to G. This change can result in different amino acids being coded for in the protein sequence.
How a change in the sequence of nucleotides in a strand of DNA might cause a protein to malfunction?
A change in the DNA sequence, such as a point mutation, can result in a different amino acid being incorporated into the protein during translation. This can alter the protein's structure, possibly affecting its function or leading to improper folding. In some cases, the mutation may introduce a premature stop codon, resulting in a truncated and non-functional protein.
What happens during a substitution mutation and how does it impact the genetic code?
During a substitution mutation, a single nucleotide in the DNA sequence is replaced with a different nucleotide. This can lead to a change in the amino acid that is coded for, potentially altering the protein that is produced. The impact on the genetic code depends on whether the substitution results in a silent mutation (no change in the amino acid) or a missense mutation (change in the amino acid), which can affect the function of the protein.
Any change or random error in DNA sequence?
A mutation is a change in the DNA sequence that can occur randomly or be induced by external factors. Mutations can range from a single nucleotide change to larger deletions or duplications. These changes can influence characteristics like protein structure and function, potentially leading to genetic disorders or other biological effects.
How can a point mutation alter the final structure of a protein?
In a point mutation, one nitrogen base is substituted for the correct base. Since most amino acids can be coded for by more than one codon, there may be no consequence to this mutation. However, sometimes a point mutation results in an incorrect amino acid being added to the amino acid sequence of the protein. This can cause a change in the shape and therefore function of the protein, which can be a harmful mutation. Two genetic disorders caused by a point mutation are cystic fibrosis and sickle cell anemia.
