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The law of complementary base pairing is violated when nucleotides do not pair according to the standard rules, which dictate that adenine pairs with thymine (or uracil in RNA) and cytosine pairs with guanine. An example of this violation can occur during mutations, such as in certain types of DNA damage or replication errors, where incorrect bases are incorporated. Additionally, in some artificial or experimental contexts, non-standard base pairing can occur, leading to mismatched or altered base interactions.

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2mo ago

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