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In eukaryotic cells, in the cytoplasm and in the mitochondria.

A small amount (2 ATP molecules per molecule of glucose) is formed in the cytoplasm. The process is called glycolysis, and does not require oxygen.

If oxygen is available, pyruvate formed during glycolysis enters the mitochondria and is there oxidized to carbon dioxide and water. The yield of ATP varies, but is probably a little below 30 molecules of ATP per glucose molecule.

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