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There have been many influenza epidemics. There are now two well-known pandemics (covers a much larger world-wide area than an epidemic or a smaller outbreak). The "Spanish Flu" pandemic was in 1918 and 50-70 million people died of the virus. The most recent pandemic was the H1N1/09 "Swine Flu" pandemic beginning in 2009 with some isolated cases still ongoing in 2012.

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