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The central dogma occurs in the nucleus, endoplasmic reticulum and golgi apparatus before the end products are exported.

Does it happpen in every cell? The short answer is yes, but for a more comprehensive answer keep reading...

However in some cases it is believed that cells can skip the first step; ie. RNA makes protein. As far as I know this occurs in platelets. However platelet RNA was made from Megakaryocyte DNA. However platelets can apparently synthesize protein without having any cellular DNA, using only RNA as a template.

In addition, in the "RNA world theory" the idea is that RNA could have been the precursor to DNA as the cells information storage medium. In these theoretical ancestral organisms the dogma would be RNA makes RNA makes protein.

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What is the newest branch to the flow chart of the central dogma?

The newest branch to the flow chart of the central dogma is the field of epigenetics. Epigenetics involves the study of changes in gene expression or cellular phenotype that are heritable and can occur without changes to the underlying DNA sequence. It provides insights into how external factors can influence gene expression and cellular function.


What is the importance of central dogma?

The central dogma of molecular biology was first enunciated by Francis Crick in 1958[1] and re-stated in a Nature paper published in 1970:[2] : The central dogma of molecular biology deals with the detailed residue-by-residue transfer of sequential information. It states that information cannot be transferred back from protein to either protein or nucleic acid. In other words, 'once information gets into protein, it can't flow back to nucleic acid.' The dogma is a framework for understanding the transfer of sequence information between sequential information-carrying biopolymers, in the most common or general case, in living organisms. There are 3 major classes of such biopolymers: DNA and RNA (both nucleic acids), and protein. There are 3×3 = 9 conceivable direct transfers of information that can occur between these. The dogma classes these into 3 groups of 3: 3 general transfers (believed to occur normally in most cells), 3 special transfers (known to occur, but only under specific conditions in case of some viruses or in a laboratory), and 3 unknown transfers (believed to never occur). The general transfers describe the normal flow of biological information: DNA can be copied to DNA (DNA replication), DNA information can be copied into mRNA, (transcription), and proteins can be synthesized using the information in mRNA as a template


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Related Questions

What is the newest branch to the flow chart of the central dogma?

The newest branch to the flow chart of the central dogma is the field of epigenetics. Epigenetics involves the study of changes in gene expression or cellular phenotype that are heritable and can occur without changes to the underlying DNA sequence. It provides insights into how external factors can influence gene expression and cellular function.


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The central dogma of molecular biology was first enunciated by Francis Crick in 1958[1] and re-stated in a Nature paper published in 1970:[2] : The central dogma of molecular biology deals with the detailed residue-by-residue transfer of sequential information. It states that information cannot be transferred back from protein to either protein or nucleic acid. In other words, 'once information gets into protein, it can't flow back to nucleic acid.' The dogma is a framework for understanding the transfer of sequence information between sequential information-carrying biopolymers, in the most common or general case, in living organisms. There are 3 major classes of such biopolymers: DNA and RNA (both nucleic acids), and protein. There are 3×3 = 9 conceivable direct transfers of information that can occur between these. The dogma classes these into 3 groups of 3: 3 general transfers (believed to occur normally in most cells), 3 special transfers (known to occur, but only under specific conditions in case of some viruses or in a laboratory), and 3 unknown transfers (believed to never occur). The general transfers describe the normal flow of biological information: DNA can be copied to DNA (DNA replication), DNA information can be copied into mRNA, (transcription), and proteins can be synthesized using the information in mRNA as a template


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