Where does the link reaction take place?

Answer 1

in the mitochondria, the pyruvate from glycolysis travels into the mitochondria and then the link reaction occurs and then the acetyl CoA is transferred into the matrix ready for the krebs cycle. Hope that helps.

Answer 2

The link reaction occurs in the matrix of the mitochondria, which is the innermost compartment of the organelle. This reaction connects glycolysis to the citric acid cycle by converting pyruvate to acetyl-CoA.