Where would you expect to find the kupffer cells of the liver and what is their function?

Answer 1

Function of Kupffer cells

Liver contains macrophages called Kupffer cells. These cells engulf and breakdown toxic matter such as microorganisms, dead cells and chemicals. Kupffer cells ingest microorganism by phagocytosis. The engulfed microorganism is called phagosome. Lysosmes in the cytoplasm of kupffer cell, fuse with the phagosome and release digestive enzymes. These enzymes breakdown and kill the microorganism.

But how does kupffer cell identify toxic matter?

There are receptors for the toxic matter on the surface of kupffer cells. The harmful particle and these receptors of kupffer cell can fit together like pieces of a puzzle. The harmful particle is then engulfed by kupffer cell.

Answer 2

Kupffer cells engulf and breakdown toxic matter such as microorganisms, dead cells and chemicals. Kupffer cells ingest microorganism by phagocytosis. The engulfed microorganism is called phagosome. Lysosmes in the cytoplasm of kupffer cell, fuse with the phagosome and release digestive enzymes. These enzymes breakdown and kill the microorganism.

Kupffer cells contain receptors for the toxic matter on the surface of kupffer cells. The harmful particle and these receptors of kupffer cell can fit together like pieces of a puzzle. The harmful particle is then engulfed by kupffer cell.

Answer 3

Kupffer cells are found in the liver sinusoids. They serve as resident macrophages and play a key role in filtering and removing foreign particles, such as bacteria and old red blood cells, from the blood passing through the liver.

Answer 4

They are located in the lining of the sinusoids and they remove debris from the blood.

Answer 5

Kupffer cells are involved in the breakdown of old Red Blood Cells which eventually forms Bilirubin. They are specialised macrophages that move about within the sinusoids of a liver lobule.

Answer 6

lines the sinusoid

removes bacteria

Answer 7

yes.