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alpha-ketoglutarate dehydrogenase is most similar to pyruvate dehydrogenase as both are enzyme complexes made of 3 units

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Which reaction in the tca cycle is a redox reaction?

In the TCA cycle (Krebs cycle), the conversion of isocitrate to alpha-ketoglutarate is a redox reaction. During this process, isocitrate is oxidized, reducing NAD+ to NADH, while a molecule of CO2 is released. This reaction is catalyzed by the enzyme isocitrate dehydrogenase, highlighting its role in facilitating the transfer of electrons in metabolic pathways.


Which step of the Krebs cycle requires both nad and ADP as reactants?

The step of the Krebs cycle that requires both NAD and ADP as reactants is the conversion of isocitrate to alpha-ketoglutarate, catalyzed by isocitrate dehydrogenase. NADH and ATP are produced in this step.


What is the third stage of the Krebs cycle?

The third stage of the Krebs cycle, also known as the citric acid cycle or TCA cycle, involves the conversion of isocitrate into α-ketoglutarate. This reaction is catalyzed by the enzyme isocitrate dehydrogenase and results in the decarboxylation of isocitrate, releasing carbon dioxide and reducing NAD+ to NADH. Additionally, this stage marks the transition of the cycle from a six-carbon compound to a five-carbon compound, further driving the cycle towards energy production.


What Krebs cycle step releases carbon dioxide?

When Pyruvic Acid is formed. The pyruvic acid molecules have one of their carbon atoms removed, in the form of CO2. The CO2 will then form coenzymes--> the enzymes that will form will continue on into the electron transport chain.


Which substances in the citric acid cycle are tricarboxylic acids?

Isocitrate, alpha-ketoglutarate, succinate, fumarate, and malate are tricarboxylic acids in the citric acid cycle.

Related Questions

What is isocitrate dehydrogenase?

Isocitrate dehydrogenase is an enzyme that plays a crucial role in the citric acid cycle, also known as the Krebs cycle. It catalyzes the conversion of isocitrate to alpha-ketoglutarate with the concomitant reduction of NAD+ to NADH. Mutations in isocitrate dehydrogenase have been associated with certain types of cancer.


What has the author R Dajani written?

R. Dajani has written: 'Regulation of isocitrate dehydrogenase in a thermophilic bacillus'


What limiting enzyme in the Krebs cycle is?

Isocitrate dehydrogenase is a key limiting enzyme in the Krebs cycle. It catalyzes the conversion of isocitrate to alpha-ketoglutarate, a critical step in the cycle.


Which step of the Krebs cycle requires both nad and ADP as reactants?

The step of the Krebs cycle that requires both NAD and ADP as reactants is the conversion of isocitrate to alpha-ketoglutarate, catalyzed by isocitrate dehydrogenase. NADH and ATP are produced in this step.


What enzymes are responsible for catalyzing the production of CO2 in cellular metabolism?

Enzymes such as pyruvate dehydrogenase, isocitrate dehydrogenase, and alpha-ketoglutarate dehydrogenase are involved in the production of CO2 in cellular metabolism through the tricarboxylic acid cycle (TCA cycle). These enzymes catalyze reactions that release CO2 as a byproduct of the conversion of carbon compounds to generate ATP.


What are the three inhibitors of tca cycle?

1.) Increases in NADH, Succinyl CoA, ATP, Citrate inhibit citrate synthase. 2.) Increases in ATP will inhibitisocitrate dehydrogenase. 3.) Increases in succinyl CoA and NADH will inhibit succinate thiokinase.


What Krebs cycle step releases carbon dioxide?

When Pyruvic Acid is formed. The pyruvic acid molecules have one of their carbon atoms removed, in the form of CO2. The CO2 will then form coenzymes--> the enzymes that will form will continue on into the electron transport chain.


How many carbon atoms in an isocitrate?

Citrate is a C6 compound i.e. there are 6 carbon atoms present in Citrate.


What are the enzymes present in mitochondria?

In outer membrane:- Monoamine oxidase, Fatty acid thiokinase, Kynurenine hydroxylase In pereimitochondrial space:- Adenylate kinase, Nucleoside diphosphokinase In inner membrane:- Succinate dehydrogenase, alpha Keto acid dehydrogenase


Which substances in the citric acid cycle are tricarboxylic acids?

Isocitrate, alpha-ketoglutarate, succinate, fumarate, and malate are tricarboxylic acids in the citric acid cycle.


What reaction does aconitase catalyse?

The isomerisation of citrate to isocitrate in the TCA cycles


Where does co2 come from during Krebs cycle?

CO2 is produced during the Krebs cycle as a byproduct of decarboxylation reactions that occur when citrate is converted to isocitrate, isocitrate to alpha-ketoglutarate, and alpha-ketoglutarate to succinyl-CoA. These decarboxylation reactions release carbon dioxide as a waste product.