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The thinning of the Southern Hemisphere's ozone layer that occurs each year is due to a lack of sunlight hitting this region. The worst "hole" that we know of occurred in 1838 due to high solar activity. There are some groups that believe that cfc's are reaching this layer and causing some issues. The problems with this concept is the levels of cfc's in the atmosphere and the location and reason for the thinning of the layer.

The group of gases that are known to degrade ozone *when sunlight strikes them*, are molecules that contain chlorine or bromine. Sunlight (less energetic than UV-B) breaks off the chlorine or bromine, they end up creating an ozone decay path, and the sunlight reactivates them.

Water vapor alone, without sunlight, will destroy ozone, and reset spontaneously to destroy ozone.

So the only "group" that contains both is "ozone depleting substances".

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