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As far as I know there is no real significant difference. Both plant and animal cells are eukaryotic cells. The simple fact that they have a nucleus separates them from prokaryotic cells. The only significant differences between the two cells I am aware of, is animal cells lack chloroplasts which enables the plant to utilize sunlight for glucose synthesis, and cell walls which gives plant cells extra support, which they need considering the high amount of osmotic pressure within the cells required to bring water and other nutrients from the roots up, against gravity, to the leaves. Plant cells also tend to have one large vacuole for stored products as opposed to the many smaller vacuoles in animal cells. I'm a senior Biology student at a university.

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