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The discovery that DNA is the chemical responsible for transforming live R cells in mice is credited to Frederick Griffith. In his 1928 experiments with Streptococcus pneumoniae, Griffith demonstrated that non-virulent R strain bacteria could be transformed into virulent S strain bacteria when exposed to heat-killed S strain. This transformative principle was later identified as DNA by Avery, MacLeod, and McCarty in 1944.

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2mo ago

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