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There's no definitive answer to this, but many biologists would argue that Biology as a subject didn't really exist before the publication of the Origin of the Species by Charles Darwin.

Biology was studied before then, but without the understanding of evolution there was little structure to it.

Another claim might be made forGottfried Reinhold Treviranus who actually coined the word "biology"; he proposed an alternative form of evolution similar to Jean-Baptiste Lamarck's theory - which was the species changed because of direct effects from the environment (for example, a giraffe stretching to reach top of a tree caused the neck to extend).

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