Captopril is not used as a prodrug. It is an active drug itself, classified as an angiotensin-converting enzyme (ACE) inhibitor used to treat hypertension and heart failure by blocking the conversion of angiotensin I to angiotensin II.
The chemical formula of captopril is C9H15NO3S.
Balsalazide-azo-bonded prodrug, activated by bacteria in the colon
In a renal scan with captopril, the patient is administered a small amount of captopril, which is a medication that helps to detect narrowing of the renal arteries. The scan is used to evaluate kidney function and assess for potential renovascular hypertension.
A prodrug becomes active when it is metabolized into its active form by the body's enzymes. This usually occurs after the prodrug is administered and travels to the site where it is converted into the active drug. Once activated, it can exert its therapeutic effect.
The half-life of the ACE inhibitor captopril is approximately 2 hours. However, this can vary among individuals due to factors such as age, kidney function, and other medications. Captopril is often taken multiple times a day to maintain its therapeutic effects due to its relatively short half-life.
The main disadvantage of captopril compared to ramipril is its shorter duration of action, which necessitates more frequent dosing. Additionally, captopril has a higher incidence of side effects such as a persistent cough and can cause skin rashes, which are less common with ramipril. Ramipril, being a prodrug, is also generally better tolerated and has a more favorable side effect profile.
The chemical formula of captopril is C9H15NO3S.
A misspelling of "captopril". Captopril is an angiotensin converting enzyme inhibitor.
The captopril test is a screening test for hypertension of kidney origin (renovascular hypertension ).
Balsalazide-azo-bonded prodrug, activated by bacteria in the colon
Captopril
In a renal scan with captopril, the patient is administered a small amount of captopril, which is a medication that helps to detect narrowing of the renal arteries. The scan is used to evaluate kidney function and assess for potential renovascular hypertension.
A prodrug becomes active when it is metabolized into its active form by the body's enzymes. This usually occurs after the prodrug is administered and travels to the site where it is converted into the active drug. Once activated, it can exert its therapeutic effect.
Prodrug for Phenobarbital.
The Captopril package insert lists hypertension as the main use for the drug. "Captopril is most commonly used to treat hypertension, but also has been used for other heart conditions such as congestive heart failure."
It is an angiotensin-converting enzyme (ACE) inhibitor
Captopril is classified as an angiotensin-converting enzyme (ACE) inhibitor. It is commonly used to treat high blood pressure, heart failure, and kidney problems.