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APC is usually associated with inheritance of a faulty gene from a parent. The APC gene is required to stop cells growing too fast: knocking out the other copy of the gene in the body (by chemical damage or random DNA damage) removes this 'brake' and allows lots of little polyps to form in the intestine.
What else can I help you with?
What happens if the apc gene is mutated?
If the APC (Adenomatous Polyposis Coli) gene is mutated, it can lead to the development of familial adenomatous polyposis (FAP), a hereditary condition characterized by the formation of numerous polyps in the colon and rectum. These polyps have a high potential to become cancerous if left untreated, significantly increasing the risk of colorectal cancer. Additionally, APC mutations can disrupt normal cell signaling pathways, contributing to tumorigenesis in various tissues. Overall, APC gene mutations have profound implications for cancer risk and tumor development.
What are the characteristics of familial polyposis?
Familial polyposis or familial adenomatous polyposis (FAP) is a premalignant disease. This means that a person with FAP, if left untreated, will invariably develop cancer. Individuals with this disorder grow hundreds of polyps.
Is FAP a sex linked genetic disease and why?
Yes, familial adenomatous polyposis (FAP) is a genetic disease caused by mutations in the APC gene, which is located on chromosome 5. While the APC gene is not located on the sex chromosomes (X or Y), FAP can be inherited in an autosomal dominant pattern, meaning that both males and females are equally likely to inherit the disease.
Does FAP follow a recessive or dominant inheritance pattern and why?
FAP follows both an autosomal recessive and autosomal dominant pattern depending on which gene you inherit the disease from. If inherited through the APC gene, which is most common, it is autosomal gdthe disease. If inherited through the MUTYH gene it is autosomal recessive, meaning that both parents were carriers of the disease or they both were living with the disease.
What is the full name of E. Coli?
Escherichia coli
Is Familial polyposis cancerous?
Hello, I see you are asking "Is Familial polyposis cancerous" Familial adenomatous polyposis (FAP) is an inherited disorder characterized by cancer of the large intestine (colon ) and rectum. People with the classic type of familial adenomatous polyposis may begin to develop multiple noncancerous (benign) growths (polyps ) in the colon as early as their teenage years. To get more info visit the url: orthopedicshealth. com/symptoms/directory/a
Who are the patients who receive ileoanal anastomosis?
Most patients--more than 85%--who undergo an ileoanal anastomosis are being treated for ulcerative colitis; familial adenomatous polyposis is the next most common condition requiring the surgery.
What happens if the apc gene is mutated?
If the APC (Adenomatous Polyposis Coli) gene is mutated, it can lead to the development of familial adenomatous polyposis (FAP), a hereditary condition characterized by the formation of numerous polyps in the colon and rectum. These polyps have a high potential to become cancerous if left untreated, significantly increasing the risk of colorectal cancer. Additionally, APC mutations can disrupt normal cell signaling pathways, contributing to tumorigenesis in various tissues. Overall, APC gene mutations have profound implications for cancer risk and tumor development.
What are the characteristics of familial polyposis?
Familial polyposis or familial adenomatous polyposis (FAP) is a premalignant disease. This means that a person with FAP, if left untreated, will invariably develop cancer. Individuals with this disorder grow hundreds of polyps.
Is there a cancer susceptibility gene found for colon cancer?
Yes, there are several forms of familial colon cancer. Several mutations are associated with multiple colon polyps that can be diagnosed with a colonoscopy. This trait is called "Familial adenomatous polyposis". Other mutations are not associated with polyps; the trait is called "hereditary non-polyposis colorectal cancer".
What treatment exists for patients with familial polyposis?
The only definitive treatment for FAP is surgical removal of the lower intestine. Since the goal is to prevent cancer, the operation is done as soon as adenomatous polyps are found on sigmoidoscopy.
Who discovered Gardner's syndrome?
It was first described in 1951 by Eldon Gardner, a college genetics teacher. It is rarely called Gardner's syndrome any more, now being considered merely one type of a genetic condition known as familial adenomatous polyposis.
What is polyectomy?
Polyectomy is a surgical procedure that involves the removal of multiple polyps, which are abnormal growths that can develop in various organs, most commonly in the colon. This procedure is often performed during a colonoscopy to prevent the potential progression of polyps into cancer. Polyectomy helps in managing conditions like familial adenomatous polyposis and other polyposis syndromes. Recovery typically depends on the number of polyps removed and the individual's overall health.
When would a temporary colostomy be done?
It is a treatment for a wide spectrum of medical conditions. It is done in congenital anomalies like spina bifida, penetrating wounds like stabs or chop wounds, crohn's disease, ulcerative colitis, other IBDs, adenomatous polyposis and carcinoma of bladder, rectum and colon.
Is FAP a sex linked genetic disease and why?
Yes, familial adenomatous polyposis (FAP) is a genetic disease caused by mutations in the APC gene, which is located on chromosome 5. While the APC gene is not located on the sex chromosomes (X or Y), FAP can be inherited in an autosomal dominant pattern, meaning that both males and females are equally likely to inherit the disease.
What is Atypical adenomatous hyperplasia?
It is the over-growth of the endometrium
What is HNPCC?
Hereditary non-polyposis colon cancer
