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Atoms combine chemically if the combined molecule has a lower overall energy than he individual atoms. In the same way that a ball rolls downhill to find the lowest point, atoms will combine (given the opportnunity) in such a way as to achieve the lowest overall energy. (As it's the electrons that take part in bonding, it's the overall energy of the electorns that matters for this, not the energy tied up in the nuclei.) And in the same way that a rolling ball may not reach the lowest level because of humps, bums and upslopes, there may be no way for a bunch of atoms to reach their lowest energy configuration without having to pass through a higher-energy intermediate state. So ammonia (NH3) has a much lower energy than hydrogen and nitrogen, but is hard to make because the atoms have to be "pushed uphill" first. It takes high pressures and temperatures to get the reaction to occur. Hydrogen and chlorine on the other hand have no such problem and need no encouragement to form hydrogen chloride.

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