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Yes,

The only thing that is not allowed to change is the number of protons (Atomic Number). Many elements have a number of 'isotopes' meaning they occur with different numbers of neutrons in the nucleus.

For example, Atomic Number = 1, Hydrogen.

It has three isotopes:

The most common, with no neutrons (Hydrogen)

With one neutron (Deuterium)

With two neutrons (Tritium)

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