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Amoebas with lobose pseudopodia, such as those in the group Amoebozoa, are classified separately from Rhizarians because of distinct morphological and genetic characteristics. Rhizarians typically have thin, filamentous pseudopodia and belong to a different evolutionary lineage. The classification reflects differences in cellular structure, locomotion, and reproductive strategies, highlighting the diversity within protists. Thus, while both groups are amoeboid, their fundamental differences warrant separate classifications.

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