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The effective half-life is always less than the biological half-life because it accounts for both biological processes (like metabolism and excretion) and physical processes (like radioactive decay, if applicable). In the case of a substance that is being eliminated from the body, the biological half-life only considers the biological elimination rate, while the effective half-life reflects the combined impact of both biological and physical elimination mechanisms. This results in a shorter effective half-life because the presence of multiple pathways for elimination leads to a more rapid overall decrease in the substance's concentration in the body.

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