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Yes. It is so. Deficiency of oxygen do not have as powerful stimulus for breathing. Carbon bi oxide is very much soluble in plasma water. In normal temperature and pressure about 900 mi of carbon bi oxide is soluble in water. Oxygen is sparingly soluble. Only about 4 ml/liter of oxygen is dissolved in water. So the respiratory center would recognize slight change in concentration of carbon bi oxide as it changes the pH of plasma also. As it is soluble in plasma it can readily enter the respiratory center cells and stimulate the center. Increase in carbon bi oxide and decrease in oxygen go hand in hand. The volume of oxygen consumed is exactly equal to the carbon bi oxide. So Nature has selected more than 200 times soluble carbon bi oxide as aindicatoras against sparingly soluble oxygen.

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You can not die of holding the breath. As you hold the breath, carbon bi oxide get accumulated in your blood. It is very powerful stimulant of the breathing.


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