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Even though around 10% of cri-du-chat patients may have gotten the deletion from a parent (if the parent has something called a balanced translocation, which does not cause problems and would not otherwise be diagnosed), it is usually a randomly occurring deletion of part of a gene. That means that it happens without a family tendency or condition, and occurs very early in fetal development. A gene which is recessive or dominant is a "whole" gene that is either expressed or not expressed in the offspring. Though it may seem like a random occurrence when you have a child with blue eyes, or red hair, those traits can be traced back through the family. Not so with a condition like cri-du-chat. It is one of those unfortunate random events that occur in nature, and can be very severe or not too severe, depending on how much genetic material is lost.

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16y ago

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