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Erythroblasts are highly radiosensitive because they are rapidly dividing cells with a high metabolic rate, making them more susceptible to damage caused by ionizing radiation. This high sensitivity is due to the DNA synthesis and mitotic activity happening in these cells, which can be disrupted by exposure to radiation, leading to cell death or malfunction.
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Is brain a most radiosensitive tissue?
The brain is not considered the most radiosensitive tissue in the body; instead, it has a relatively low sensitivity to radiation compared to other tissues, such as bone marrow or the gastrointestinal tract. The central nervous system, particularly neurons, has limited capacity for regeneration, which can make damage from radiation more critical. However, glial cells, which support neurons, can be more affected by radiation. Overall, while the brain can be impacted by radiation exposure, it is not the most radiosensitive tissue.
Which is the most radiosensitive structure in human body?
The bone marrow is considered the most radiosensitive structure in the human body because it contains blood-forming stem cells that divide rapidly and are sensitive to radiation damage. Impairment of bone marrow function can lead to decreased blood cell production and increased susceptibility to infections and bleeding.
What is a hemoglobin depleted red blood cell called?
erythroblasts
What happens in basophilic erythroblast?
Basophilic erythroblasts are immature red blood cells in the bone marrow that contain basophilic granules, which are a type of cytoplasmic organelle. These granules are involved in the synthesis of hemoglobin, which is essential for oxygen transport in the body. Basophilic erythroblasts eventually mature into erythrocytes (red blood cells) as they progress through stages of development in the bone marrow.
Where is hemoglobin synthesized?
Hemoglobin is primarily synthesized in red blood cells in the bone marrow. The production of hemoglobin involves a series of steps that require iron, amino acids, and various vitamins and minerals. The synthesis of hemoglobin is tightly regulated to ensure proper oxygen transport throughout the body.
Which phase of cell cycle is most radiosensitive?
Metaphase
What area of the eye is the most radiosensitive?
lens cataracts could develop from damage to the lens.
Is brain a most radiosensitive tissue?
The brain is not considered the most radiosensitive tissue in the body; instead, it has a relatively low sensitivity to radiation compared to other tissues, such as bone marrow or the gastrointestinal tract. The central nervous system, particularly neurons, has limited capacity for regeneration, which can make damage from radiation more critical. However, glial cells, which support neurons, can be more affected by radiation. Overall, while the brain can be impacted by radiation exposure, it is not the most radiosensitive tissue.
What is a hemoglobin depleted red blood cell called?
erythroblasts
Which is the most radiosensitive structure in human body?
The bone marrow is considered the most radiosensitive structure in the human body because it contains blood-forming stem cells that divide rapidly and are sensitive to radiation damage. Impairment of bone marrow function can lead to decreased blood cell production and increased susceptibility to infections and bleeding.
Which are the most radiosensitive blood cells?
Immature, undifferentiated, dividing cells, for example: White blood cells and sperm cells.
Which is radiosensitive tumor?
Lymphoma multiple myeloma seminoma wilms ewings medulloblastoma
Blood cells and platelets are produced in the red marrow?
Erythroblasts
What do proerythroblasts eventually become?
Proerythroblasts eventually differentiate into basophilic erythroblasts, which are precursor cells in the process of red blood cell formation. Through several stages of maturation, basophilic erythroblasts will ultimately develop into mature red blood cells.
Is erythroblast the same as formation of red cells?
Not exactly, but erythroblasts are the precursors of red blood cells.
What happens in basophilic erythroblast?
Basophilic erythroblasts are immature red blood cells in the bone marrow that contain basophilic granules, which are a type of cytoplasmic organelle. These granules are involved in the synthesis of hemoglobin, which is essential for oxygen transport in the body. Basophilic erythroblasts eventually mature into erythrocytes (red blood cells) as they progress through stages of development in the bone marrow.
What makes tumor cells radiosensitive?
Simply: tumor cells tend to be more radiosensitive because they spend more time on average undergoing uncontrolled mitosis than normal cells. Since mitosis is the most sensitive phase of the cell cycle (phase through which the cell is most easily lethally damaged by radiation), their risk is increased. On another note, depending on which genes are causing the cell to become cancerous, certain blockers that would prevent a cell whose DNA had been damaged by radiation might not stop that cell from moving into mitosis, failing, and committing apoptosis (preprogrammed cell death).
