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Endoplasmic reticulum (ER) or more specific rough endoplasmic reticulum is important due to the presence of ribosomes on the surface of ER.
The protein synthesis takes place in the ribosomes but once its "completed" it moves within the interior of the ER.
Now ER is important because although the protein synthesis is done still some modifications is required to activate it. A portion of modification is done inside the ER where proteins ( eg. Insulin) are a step closer for activation.
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What else can I help you with?
Which organelles are responsible for the synthesis insulin?
Rough endoplasmic reticulum. The peptide bonds are actually formed by an structure called a ribosome. This is capable of making peptide bonds whether it is attached to the endoplasmic reticulum or free floating in the cytoplasm - but it isn't a organelle. However, the rough endoplasmic reticulum is a membrane-bound organelle which has a surface which is studded with ribosomes.
What is a internal organ that produces insulin?
pacreas The "pancreas" is and ORGAN. Organelles and organs are two different things. The organelles responsible for the production of insulin are the nucleus, rRNA, golgi, and rough endoplasmic reticulum.
What is the targeting pathway of insulin?
Endoplasmic Reticulum --> Golgi Apparatus --> outside the cell
Which proteins are synthesized by bound ribosomes?
Yes, where? The first R in 'RER' stands for rough as in 'rough endoplasmic reticulum'. Compare this to 'SER' - smooth endoplasmic reticulum. Yes, the rough designation reflects the existence of endoplasmic bound ribosome entities/particles that are the main sites of cellular protein synthesis.
Why do some cells of the human pancreas have up to 100 times the amount of endoplasmic reticulum as other parts of the body?
The pancreas secretes the hormones insulin, glucagon, and somatastatin, and the digestive enzymes, lipase, protease, and amylase. Proteins that will be secreted by the cell are produced by the ribosomes on the rough endoplasmic reticulum. Therefore, cells that secrete proteins have a large amount of rough endoplasmic reticulum.
What would be the effects of adding the sequence KDEL to insulin?
KDEL an amino acid sequence which signals that a protein belongs in the endoplasmic reticulum. Attaching it to insulin would cause the insulin to be retained within the endoplasmic reticulum.
Which organelles are responsible for the synthesis insulin?
Rough endoplasmic reticulum. The peptide bonds are actually formed by an structure called a ribosome. This is capable of making peptide bonds whether it is attached to the endoplasmic reticulum or free floating in the cytoplasm - but it isn't a organelle. However, the rough endoplasmic reticulum is a membrane-bound organelle which has a surface which is studded with ribosomes.
What is a internal organ that produces insulin?
pacreas The "pancreas" is and ORGAN. Organelles and organs are two different things. The organelles responsible for the production of insulin are the nucleus, rRNA, golgi, and rough endoplasmic reticulum.
Real life examples of endoplasmic reticulum?
Some real-life examples of the endoplasmic reticulum (ER) in action include the production of proteins in cells, such as insulin in pancreas cells, and the detoxification of drugs and toxins in liver cells. Additionally, the ER plays a crucial role in lipid metabolism in cells, which is important for membrane synthesis and energy storage.
What is the targeting pathway of insulin?
Endoplasmic Reticulum --> Golgi Apparatus --> outside the cell
Which proteins are synthesized by bound ribosomes?
Yes, where? The first R in 'RER' stands for rough as in 'rough endoplasmic reticulum'. Compare this to 'SER' - smooth endoplasmic reticulum. Yes, the rough designation reflects the existence of endoplasmic bound ribosome entities/particles that are the main sites of cellular protein synthesis.
What is the route of insulin from its production to its exit from the cell?
The route of the insulin from its production to its exit from the cell is at the pancreatic cells. This is then secreted in the bloodstream.
What structure is responsible for synthesis of steroids?
The endoplasmic reticulum, specifically the smooth endoplasmic reticulum, is responsible for the synthesis of steroids in cells. This organelle contains enzymes necessary for the synthesis of cholesterol, the precursor to steroid hormones.
Why do some cells of the human pancreas have up to 100 times the amount of endoplasmic reticulum as other parts of the body?
The pancreas secretes the hormones insulin, glucagon, and somatastatin, and the digestive enzymes, lipase, protease, and amylase. Proteins that will be secreted by the cell are produced by the ribosomes on the rough endoplasmic reticulum. Therefore, cells that secrete proteins have a large amount of rough endoplasmic reticulum.
What substances are produced at the surface of the Endoplasmic Reticulum of a cell?
Pepsin is produced by cells lining the stomach and released into the stomach cavity. Insulin is made by pancreatic cells & released into the bloodstream.
When a large proportion of cell's ribosomes attached to the endoplasmic reticulum it is a sign that the cell is specialized to what?
When a large proportion of a cell's ribosomes are attached to the endoplasmic reticulum, it is a sign that the cell is specialized for protein synthesis and secretion. The rough endoplasmic reticulum plays a vital role in synthesizing and modifying proteins for secretion to other parts of the cell or outside the cell. This specialization is common in cells that produce a large amount of proteins for export, such as pancreatic cells producing insulin.
What cell has a lot of rough endoplasmic reticulum?
Cells that are involved in protein synthesis, such as pancreas cells that produce insulin, have a large amount of rough endoplasmic retriculum. The rough ER is responsible for synthesizing and processing proteins before they are transported to their final destination within the cell or outside the cell.
