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Main group organometallics are not widely used as catalysts in organic synthesis primarily due to their high reactivity and instability. These compounds often undergo decomposition or side reactions, which can lead to inconsistent results. Additionally, their selectivity and efficiency in catalyzing reactions are generally inferior to those of transition metal catalysts, which offer better control over reaction conditions and mechanisms. As a result, chemists often prefer more stable and effective transition metal catalysts for synthetic applications.

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