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ASA (acetylsalicylic acid) or Aspirin is synthesised by reacting Salicylic Acid with Acetic Anhydride. During this esterification, the dehydration occurs on the hydroxyl group attached to the benzene ring. As a result, the product no longer possesses the Phenol functional group.
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Why is salicylic acid more acidic than acetylsalicylic acid?
Salicylic acid dissociates in water to form a carboxylic acid group, making it more acidic compared to acetylsalicylic acid which has an ester group that is less acidic. The presence of the -OH group in salicylic acid contributes to its higher acidity compared to the -OR group in acetylsalicylic acid.
What is the formula for acetylsalicylic acid?
The chemical formula for acetylsalicylic acid is C9H8O4.
Which is stronger acid ethanol or phenol?
Phenol is stronger acid than ethanol. Phenol's acidic strength stems from the presence of the -OH group attached directly to the aromatic ring, which allows it to readily donate a proton. Ethanol, in contrast, has a less acidic -OH group due to its aliphatic structure.
What is the only organic acid without COOH group?
There are several organic acids without COOH group , example is carbolic acid , a phenol, picric acid which is 2,4,6 tri-nitro phenol, barbituric acid, ascorbic acid etc
By What name the acetylsalicylic acid better known?
Acetylsalicylic acid is better known as aspirin.
Why acylation occur at phenol rather than carboxylic acid in salicylic acid?
Acylation occurs at the phenol group in salicylic acid due to the higher reactivity of the phenol hydroxyl group compared to the carboxylic acid group. The phenol group is more nucleophilic and readily reacts with acetyl chloride to form acetylsalicylic acid (aspirin). Additionally, the carboxylic acid group can interfere with the reaction due to its ability to form hydrogen bonds, making it less reactive towards acylation.
Why is salicylic acid more acidic than acetylsalicylic acid?
Salicylic acid dissociates in water to form a carboxylic acid group, making it more acidic compared to acetylsalicylic acid which has an ester group that is less acidic. The presence of the -OH group in salicylic acid contributes to its higher acidity compared to the -OR group in acetylsalicylic acid.
Is phenol an acid?
Yes, phenol is a weak acid due to the presence of a hydroxyl group (OH) that can dissociate and release a proton. This makes phenol capable of reacting with bases to form salts.
What is the formula for acetylsalicylic acid?
The chemical formula for acetylsalicylic acid is C9H8O4.
Which is stronger acid ethanol or phenol?
Phenol is stronger acid than ethanol. Phenol's acidic strength stems from the presence of the -OH group attached directly to the aromatic ring, which allows it to readily donate a proton. Ethanol, in contrast, has a less acidic -OH group due to its aliphatic structure.
What is the only organic acid without COOH group?
There are several organic acids without COOH group , example is carbolic acid , a phenol, picric acid which is 2,4,6 tri-nitro phenol, barbituric acid, ascorbic acid etc
Can you take Aleve with acetylsalicylic acid?
No advid does not contail acetylsalicylic acid. Only Bayer and aspirin.
By What name the acetylsalicylic acid better known?
Acetylsalicylic acid is better known as aspirin.
Simple explanation on how salicylic acid acetyl is made?
Salicylic acid acetyl is made by reacting salicylic acid with acetic anhydride in the presence of an acid catalyst, such as sulfuric acid, to form acetylsalicylic acid. This reaction causes the hydroxyl group (-OH) of salicylic acid to be acetylated, resulting in acetylsalicylic acid, commonly known as aspirin.
Can you get phenol from carbolic acid?
Phenol and carbolic acid are actually the same compound. "Carbolic acid" is an older, colloquial term for phenol.
What name is acetysalicyclic acid better known?
Acetylsalicylic Acid is better known as asprin.
What are the key spectral features observed in the NMR spectrum of acetylsalicylic acid?
In the NMR spectrum of acetylsalicylic acid, key spectral features include peaks corresponding to the aromatic protons in the benzene ring, the acetyl group, and the carboxylic acid group. These peaks typically appear in distinct regions of the spectrum, allowing for identification of the compound.
