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The holes suggested that there were "missing" elements that hadn't been discovered yet. Mendeleev successfully predicted the basic properties of germanium, which hadn't been discovered at the time, based on the properties he expected an element in that position to have. He called it "eka-silicon" (eka is a Sanskrit word meaning "one", because it was one period "higher" than silicon).

When germanium was later discovered and turned out to have properties very similar to what Mendeleev had predicted, it went a long way towards validating Mendeleev's concept.

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