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In 1964, scientists at the Belgian pharmaceutical company UCB synthesised a substance now known as Piracetam. Dr. Corneliu E. Giurgea, who led the team that synthesized Piracetam, coined the new substance a "Nootropic" and later branded the product Nootropil. The scientists were amazed at the safety of Piracetam, even in large doses. They observed the ability of Piracetam to increase mental functioning both in healthy people and in individuals with diseased mental conditions, such as Alzheimer's and dementia. Dr. Giurgea came up with a set of criteria that substances had to meet in order to be considered a true nootropic.

  1. The substance enhances learning and memory
  2. The substance enhances learned behaviours under conditions which are known to
  3. disrupt them (hypoxia, for example)
  4. The substance protects the brain from chemical or physical injury
  5. The substance enhances the tonic cortical/subcortical control mechanisms
  6. The substance exhibits few side effects and extremely low toxicity, while also lacking
  7. the pharmacology of typical psychotropic drugs (motor stimulation, sedation, etc.)

Piracetam met all of these criteria and was subsequently the first substance labeled as a nootropic. Soon, many other compounds were derived from this new family of drugs called Racetams. From Piracetam, other Racetams such as Oxiracetam, Aniracetam, and Pramiracetam were developed and touted to be even more potent than the previous derivative. While each of the Racetams provide differing solubilities and potencies, they vary little in their effects. No one has been able to identify the exact mechanism of how Piracetam positively influences memory, but it is generally accepted that it enhances cerebral blood flow and protects brain cells from damage from oxygen deprivation. It is also said to increase communication between the left and right hemispheres of the brain through stimulation of the corpus callosum. In terms of safety, Piracetam has little, if any, side effects. One scientist said that it was safer than salt and described the potential side effects as "few, mild, and transient."

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Related Questions

Are nootropics legal in UK?

The legal status of nootropics in the UK varies depending on the specific substance. While many natural nootropics like Ginkgo Biloba and Rhodiola Rosea are legal and readily available, some synthetic nootropics, such as Modafinil and certain racetams, are regulated and may require a prescription. It's important to check the specific regulations for each nootropic you're interested in. For a detailed overview of nootropics and their legal status, you can visit this comprehensive guide.


Where to get Nootropics without a prescription?

Genuine FDA-approved Nootropics are available at the best price at Health Matter. One can get Nootropics without a prescription from the Health Matter online pharmacy. It offers popular Nootropics to treat sleep disorders and mental health issues. People who are looking for affordable Nootropic, health Matter is the best platform. healthmatter.co/


How much of and how often should you take Piracetam for it to be effective?

You need to take at least 800mg per dosage. Piracetam is most effective when combined with other nootropics.


What exists for experimental treatment for dementia?

There is encouraging research that nootropics can be used to treat dementia. Nootropics are branch of vitamins that target brain health and chemical stability.


Where is Piracetam sold?

I would try PROFIDERALL. You can buy it online and it combines Piracetam with a bunch of other nootropics. It is basically a natural alternative to adderall.


What drugs speeds up neural activity by increasing the body's production of epinephrine?

ventoline


Do nootropic drugs have health risks?

Always do your homework before taking a new substance. Most Nootropics are generally regarded as safe (GRAS) but none are approved to treat or cure any illness or disease. For a healthy person looking to gain an edge in school or life, Piracetam is the gold standard and the first nootropic you should start with. Many see an immediate effect but for most it may take weeks or months to notice a difference. Generally, the healthier you are the less noticeable the effects. Be sure to give ample time before discrediting Nootropics. Nootropics build with time so you're more likely to see a difference after six months than you are after three. The longer you take it, the more the effects build.


What are the benefits of incorporating L-Theanine into a stack of nootropics for cognitive enhancement?

L-Theanine, when added to a nootropic stack, can help improve focus, reduce anxiety, and enhance cognitive performance. It works well with other nootropics to promote a calm and alert state of mind, making it easier to concentrate and think clearly.


What is the limitless pill?

The limitless pill, NZT-48, is the fictional cognitive enhancer Bradley Cooper used to become a genius in 2011 Hollywood movie, Limitless. Obviously, the film exaggerated the effects of the pill for the sake of entertainment. Genius pills like that do not exist in the real world. However, nootropics do exist. Nootropics are vital nutrients for your brain, similar to workout supplements for your body. Other prescription smart drugs have become popular since the movie such as Adderall and Modafinil, but if you're looking for something all natural, stick to nootropics.


How do smart drugs work?

Nootropics or "smart drugs" improve the function of the neurotransmitter acetylcholine via muscarinic cholinergic (ACh) receptors which are implicated in memory processes. Furthermore, they have an effect on NMDA glutamate receptors which are involved with learning and memory processes. Nootropics influence neuronal and vascular functions and increase cognitive function, while at the same time providing a natural source of energy to keep you alert and motivated.


Can you take Prevagin and IQ?

Both are advertised as brain enhancers, helping people do better on mental tasks. Basically Prevagin and Brain Plus IQ are the same in the class of nootropics. The FDA claims that the key ingredient of Prevagin, apoaequorin, a synthetic protein, is not an acceptable ingredient in a dietary supplement. Limited use, if any, seems to be a wise choice and choose one or the other. A good resource would be a pharmacist or your doctor.


Where can you buy profideral or Addrena or Add Fabz and which one is a better stimulant?

Addrena is easily the most powerful stimulant and also contains the most amount of Nootropics. Just start your dose low.