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Bluish-purple skin can be indicative of a genetic disorder known as methemoglobinemia, where an abnormal amount of methemoglobin—a form of hemoglobin that cannot effectively release oxygen to tissues—accumulates in the blood. This condition can be inherited or acquired and results in a characteristic skin discoloration known as cyanosis. Other genetic disorders that might cause similar symptoms could include certain forms of Ehlers-Danlos syndrome or hereditary hemorrhagic telangiectasia, but methemoglobinemia is the most directly associated with bluish-purple skin.

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