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Creating an environment similar to the cytoplasm to sustain mitochondria is theoretically feasible. Researchers can replicate key characteristics of the cytoplasm, such as pH, ionic strength, and nutrient availability, using biochemical solutions. However, maintaining mitochondrial function outside their natural cellular context poses challenges, including energy supply and the need for various cofactors and proteins. While advances in synthetic Biology and bioengineering may facilitate this, fully sustaining mitochondria in vitro remains a complex task.

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3mo ago

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