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Yes, some can be seen by the naked eye.

While the vast majority of cells are far too small to be seen without at least a magnifying glass, many species of single-celled organisms are in fact large enough to be seen by the naked eye. The human eye is able to perceive cells as small as parameciums, under the proper lighting, but single-celled organisms can indeed grow much larger still. The yolk of eggs, for example, is a single haploid cell that is ordinarily fertilized by a spermatazoa. Single celled protozoans the size of grapes have been found crawling along the ocean floor, and larger still is the Caulerpa, a plant-like single-celled algae that develops multiple nuclei and grows leaf-like fronds, and can develop up to a length of thirty to ninety inches, or up to one to three meters in length. The odds are good that you have seen a Caulerpa sometime during your life, as they are a common species of seaweed that is very popular in domestic aquariums.

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