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In imaging studies, contrast media is used to enhance visualization of anatomical structures. Double contrast involves using both positive and negative contrast agents to highlight different tissues or structures in the body, such as in barium enemas. Single contrast only uses one type of contrast agent, typically a positive agent, to highlight specific structures of interest, like in a barium swallow. Double contrast provides more detailed information but requires more time and expertise to interpret, while single contrast is simpler and quicker but may offer less detail.

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