answersLogoWhite

0

How do MAOIs work?

Updated: 4/28/2022
User Avatar

Wiki User

15y ago

Best Answer

Stopping an enzyme called monoamine oxidase from working. These break down things known as monoamines (dopamine, serotonin, noradrenaline) so by blocking them you raise levels of these monoamines especially in the brain, used to treat depression.

However by blocking the endogenous enzymes, you can't eat too much of a monoamine called tyramine (found in beer, cheese, wine etc) otherwise you get the 'cheese effect', where you have a medical emergency known as a hypertensive crisis forming. For this reason, MAOIs are being phased out except for certain types of atypical depression in the UK, being replaced by SSRIs and SNRIs that are much more selective.

User Avatar

Wiki User

15y ago
This answer is:
User Avatar

Add your answer:

Earn +20 pts
Q: How do MAOIs work?
Write your answer...
Submit
Still have questions?
magnify glass
imp
Related questions

Maoi interact with nitrous oxide?

MAOIs do not interact with nitrous oxides. MAOIs affect monoamine compounds. Nitrous oxide is not one of these, so MAOIs do not affect the activity of nitrous oxide.


Which country gave us the word kiwi?

Maois


How do you treat the cheese reaction caused by MAOIs?

give alpha-blocker (e.g. phentolamine, prazosin)


Which antidepressant that might cause cheese reaction as its side effect?

monoamine oxidase inhibitors (MAOIs)


What will happen if you combine shrooms and an anti deppresant They are the Panaeolus cyanescens and it is a MAOIs anti-dep Will it be a good mix or bad mix?

MAOIs can greatly potentiate the effects of magic mushrooms, possibly leading to an overly intense experience. Thus, such a combination is strongly discouraged.


Is Xanax an maoi inhibitor?

Alprazolam (Xanax) is not in the list of drugs classified as monoamine oxidase inhibitors (MAOIs). For a list of antidepressants classified as MAOIs, see the related links section. No, it doesn't contain an MAOI. Xanax (alprazolam) is a benzodiazepine


Which antidepressant that has amphetamine stimulant effect as its side effect?

Tranylcypromine (a reversible MAOIs). This drug can lead to insomnia and agitation.


Is Pamelor an maoi?

No. It's an SSRI (selective serotonin reuptake inhibitor), a "safer" class of antidepressants than MAOIs (monoamine oxidase). Paxil acts on one specific neurotransmitter in the brain (serotonin) wereas MAOIs act on several neurotransmitters (serotonin, dopamine, noradrenaline, and other amines).


What are themedication for depression?

Antidepressants: SSRIs, MAOIs, and tricyclics are three major categories of antidepressants. SSRIs are the most common and include Celexa, Zoloft, and Lexapro among others.


What is the word maize when translated form English to Gailic?

Irish Gaelic: min bhuí or arbhar indiach.Scottish Gaelic: maois, min Innseanach, cruithneacht Innseanach, coirce-milis.


With what medications may zonisamide may have negative interactions?

Zonisamide may have negative interactions with some antifungal medications, antihistimines, antidepressants, antibiotics, and monoamine oxidase inhibitors (MAOIs).


With what medications may modafinil have negative interactions?

Modafinil may have negative interactions with some anticoagulants (blood thinners), antidepressants, antifungals, antibiotics, and monoamine oxidase inhibitors (MAOIs).