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Marfan's syndrome is the hormonal disorder that can cause enlargement of the extremities. Acromegaly is the medical term meaning enlargement of the extremities.

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What are the disorders of the endocrine system?

Acromegaly (ak-ro-MEG-ah-lee): Disorder in which the anterior pituitary overproduces growth hormone, resulting in abnormal enlargement of the extremities-nose, jaw, fingers, and toes; in children, the disorder produces gigantism.Addison's disease (ADD-i-sonz): Disorder in which the adrenal cortex underproduces cortisol and aldosterone, resulting in the disruption of numerous bodily functions.Cushing's syndrome (KU-shingz SIN-drome): Disorder caused by an overproduction of steroids (mostly cortisol) by the adrenal cortex, resulting in obesity and muscular weakness.Diabetes mellitus (die-ah-BEE-teez MUL-le-tus): Disorder in which the body's cells cannot absorb glucose, either because the pancreas does not produce enough insulin or the cells do not respond to the effects of insulin that is produced.Gigantism (jie-GAN-tizm): Disorder in children in which the anterior pituitary overproduces growth hormone, resulting in abnormal enlargement of the extremities (nose, jaw, fingers, and toes) and the long bones, causing unusual height.Hyperthyroidism (hi-per-THIGH-roy-dizm): Disorder in which an overactive thyroid produces too much thyroxine.Hypothyroidism (hi-po-THIGH-roy-dizm): Disorder in which an underactive thyroid produces too little thyroxine.


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Cryoglobulinemia


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What is the volume of blood in the extremities?

This depends on the external temperature of the human in question. The colder they are, the less volume is found in the extremities. However, the volume is considered high, because an injury causing blood loss in the limbs can cause someone to die in a few minutes without medical attention.


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During exercise, blood flow to the extremities is reduced because the body prioritizes delivering oxygen-rich blood to the muscles that are actively working. The sympathetic nervous system is activated, causing vasoconstriction in the blood vessels of the extremities while promoting vasodilation in the muscles. This redistribution ensures that the essential muscles receive adequate blood supply to support increased metabolic demands during physical activity. As a result, extremities may receive less blood flow temporarily.


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Why do pregnant women often experience numbness in their fingers and toes?

During pregnancy, hormonal changes can lead to increased fluid retention in the body, which can put pressure on nerves and blood vessels, causing numbness in the fingers and toes. Additionally, the growing uterus can compress nerves in the lower back, further contributing to numbness in the extremities. Adequate rest, gentle stretching, and avoiding prolonged standing or sitting can help alleviate these symptoms.