The formulation of sustained-release rectal suppositories involves selecting appropriate excipients that facilitate prolonged drug release while ensuring stability and bioavailability. Commonly used bases include hydrophilic polymers (e.g., polyethylene glycol) or lipid-based carriers (e.g., cocoa butter) that can control the release rate. Active pharmaceutical ingredients are usually combined with these bases, and additives like stabilizers or surfactants may be included to enhance solubility and absorption. The final formulation is then shaped into suppository molds and evaluated for consistency, release profile, and efficacy.
The rectal suppository for nausea that must be refrigerated is often ondansetron (Zofran) in its suppository form. This medication is used to prevent nausea and vomiting, particularly in patients undergoing chemotherapy or surgery. Due to its formulation, it is recommended to store it in the refrigerator to maintain its efficacy and stability. Always follow specific storage instructions provided by the manufacturer or as directed by a healthcare professional.
No since the suppository is absorbed through the rectal mucosa.
No
Reinforce a dressing
Yes
no
Almost anyone (depending on the drug) can administer a rectal suppository.There are many people who self administer them.
No, Phenergan is not a patch; it is an antihistamine medication that is primarily available in oral tablet, liquid, and injectable forms. It is used to treat symptoms such as allergies, motion sickness, and nausea. There is also a rectal suppository formulation, but it does not come in patch form.
A suppository is a pill or medication that is inserted through the rectal area of the body. A suppository can be introduced into any absorbent orifice of the body,such as the vagina.
Inserting pills into the anus is called rectal administration or rectal drug delivery. It involves placing medication in the rectum for absorption into the bloodstream. It is also known as rectal suppository insertion.
Diarrhea is not a contra indication for rectal paracetamol. But if the child passes stool as soon as you keep the suppository it may be expelled.
No, you should not swallow a 25mg promethazine suppository. Suppositories are specifically designed for rectal administration and are formulated to dissolve and be absorbed in the rectal area, not the digestive system. Swallowing it could lead to improper absorption and potential gastrointestinal irritation. Always follow the administration guidelines provided by a healthcare professional.