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When retinoblastoma protein (Rb) is phosphorylated, it undergoes a conformational change that inactivates its ability to bind to E2F transcription factors. This release of E2F allows for the transcription of genes necessary for cell cycle progression, particularly the transition from the G1 phase to the S phase. As a result, the cell is enabled to proliferate and divide. Phosphorylation of Rb is a crucial regulatory step in the cell cycle, particularly in response to growth signals.
What else can I help you with?
What happens once glucose is phosphorylated?
Becomes trapped in the cell
What happens to the phosphorylated glucose in glycolysis?
Glutamic acid covalently bonded with a phosphate group
Can aspartic acid be phosphorylated in biological systems?
Yes, aspartic acid can be phosphorylated in biological systems.
Which amino acids can be phosphorylated in biological systems?
In biological systems, amino acids such as serine, threonine, and tyrosine can be phosphorylated.
Which protein can be phosphorylated by protein kinase AA?
The protein that can be phosphorylated by protein kinase AA is called protein X.
Can aspartate be phosphorylated in biological systems?
Yes, aspartate can be phosphorylated in biological systems through the addition of a phosphate group to its structure.
Describe what happens where during the first step of glycolysis?
during the first step of glycolysis C6 is phosphorylated, turning it into a phosphate ester which is a low energy compound.
Differences between primary and secondary active transport?
In primary active transport, the transport protein gets phosphorylated; in secondary active transport, the transport protein is not phosphorylated
What period is the element rb in the periodic table?
Rb is the symbol for the element, rubidium.
Which amino acid is phosphorylated in bacterial proteins?
his, asp,ser,thr
What does Contemporary RB mean?
RB as it is at this time
What is the value of a RB 1979 nickel?
RB ???
